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Exosome-Mediated Drug Delivery for Brain Tumors: Exploiting Natural BBB Transcytosis for Glioblastoma Treatment
Glioblastoma multiforme remains one of the most devastating diagnoses in oncology. Despite aggressive treatment, median survival barely exceeds 15 months. A primary driver is the blood-brain barrier, preventing over 95% of therapeutics from reaching tumor cells. Exosome-mediated drug delivery is emerging as the most promising strategy to breach this barrier. The Blood-Brain Barrier: Obstacle and…